Title: Ethnic variations in dementia: the contributions of cardiovascular, psychosocial and neuropsychological factors
year: 2010
Journal: Dement Geriatr Cogn Disord
Volume: 29
Issue: 2
Pages: 131-8
Epubdate: 11/02/2010
Alternate Journal: Dementia and geriatric cognitive disorders
ISSN: 1420-8008
DOI: 10.1159/000275668
Accession Number: 20145399
Abstract: BACKGROUND: Ethnic variations in dementia rate have been reported worldwide. Understanding these differences is vital for aetiological research, clinical care and health service planning. While age and gender have been consistently implicated, the reasons behind interethnic variation remain unclear. METHOD: We used data from the Singapore National Mental Health Survey (Elderly) in 2003, a cross-sectional population-based study to investigate the extent to which differences in cardiovascular risk factors, psychosocial factors and cognitive functional status contributed to ethnic differences in dementia prevalence among Chinese, Malays and Indians. RESULTS: Ethnic differences in dementia prevalence (4.2% in Chinese, 9.4% in Malays and 8.8% in Indians) were not explained by differences in gender, age and education (Malays vs. Chinese: adjusted OR = 3.11; Indians vs. Chinese: OR = 4.30). Differences in cardiovascular factors, depression or leisure time activities contributed modestly to the differences, but the OR remained significantly elevated. Differences in Mini-Mental State Examination scores contributed the most to explaining the ethnic differences (Malays vs. Chinese: adjusted OR = 0.73; Indians vs. Chinese: OR = 1.18). CONCLUSION: Cognitive functional reserve accounted for much of the ethnic differences in dementia prevalence and its assessment has implications for the detection and treatment of dementia in multiethnic populations.
URI: https://open-access.imh.com.sg/handle/123456789/4486
Authors Address: Gerontological Research Programme
Faculty of Medicine
National University of Singapore
Singapore. pcmngtp@nus.edu.sg
Database Provider: NLM
language: eng
Appears in Collections:2010

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