Title: A Brain-Computer Interface Based Attention Training Program for Treating Attention Deficit Hyperactivity Disorder
year: 2012
Journal: PLoS ONE
Volume: 7
Issue: 10
Pages: e46692
DOI: 10.1371/journal.pone.0046692
Abstract: <p>Attention deficit hyperactivity disorder (ADHD) symptoms can be difficult to treat. We previously reported that a 20-session brain-computer interface (BCI) attention training programme improved ADHD symptoms. Here, we investigated a new more intensive BCI-based attention training game system on 20 unmedicated ADHD children (16 males, 4 females) with significant inattentive symptoms (combined and inattentive ADHD subtypes). This new system monitored attention through a head band with dry EEG sensors, which was used to drive a feed forward game. The system was calibrated for each user by measuring the EEG parameters during a Stroop task. Treatment consisted of an 8-week training comprising 24 sessions followed by 3 once-monthly booster training sessions. Following intervention, both parent-rated inattentive and hyperactive-impulsive symptoms on the ADHD Rating Scale showed significant improvement. At week 8, the mean improvement was ?4.6 (5.9) and ?4.7 (5.6) respectively for inattentive symptoms and hyperactive-impulsive symptoms (both p<0.01). Cohen?s d effect size for inattentive symptoms was large at 0.78 at week 8 and 0.84 at week 24 (post-boosters). Further analysis showed that the change in the EEG based BCI ADHD severity measure correlated with the change ADHD Rating Scale scores. The BCI-based attention training game system is a potential new treatment for ADHD.</p><sec><title>Trial Registration</title><p>ClinicalTrials.gov <ext-link xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="uri" xlink:href="http://clinicaltrials.gov/ct2/show/NCT01344044" xlink:type="simple">NCT01344044</ext-link></p></sec>
URL: http://dx.doi.org/10.1371%2Fjournal.pone.0046692
URI: https://open-access.imh.com.sg/handle/123456789/4565
Appears in Collections:2012




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