|Title:||Validated five-factor model of positive and negative syndrome scale for schizophrenia in Chinese population|
|Alternate Journal:||Schizophrenia research|
|Abstract:||The Positive and Negative Syndrome Scale (PANSS) is the most widely used instrument to assess the severity of symptoms of schizophrenia. Most studies have showed that PANSS measures five dimensions of symptomatology of schizophrenia. However, few studies have ever investigated the structure of PANSS in Chinese schizophrenia population. We recruited two large independent study samples including 903 and 942 Chinese schizophrenia patients and examined the underlying structure of PANSS. By building a confirmatory factor analysis (CFA) model based on the factor loadings of the exploratory factor analysis (EFA) and by testing the CFA model in an independent validation sample, we found that PANSS scores consisted of five factors, which were positive factor, negative factor, excitement factor, depression factor, and cognitive factor. The items loaded on these factors were similar to the consensus items published in previous studies except for PANSS items P2 conceptual disorganization, P5 grandiosity, N5 abstract thinking, and G11 poor attention. This difference might be due to the influence of culture on clinical presentation of schizophrenia. By elucidating the structure, symptoms of Chinese schizophrenia patients could possibly be deconstructed and investigated in future studies.|
Research Support, Non-U.S. Gov't
Schizophr Res. 2013 Jan
143(1):38-43. doi: 10.1016/j.schres.2012.10.019. Epub 2012 Nov 11.
|Authors Address:||Research Division, Institute of Mental Health/Woodbridge Hospital, Singapore; Saw Swee Hock School of Public Health, National University of Singapore, Singapore.|
|Appears in Collections:||2013|
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