|Title:||Predictive utility of blood pressure, waist circumference and body mass index for metabolic syndrome in patients with schizophrenia in Singapore|
|Journal:||Early Interv Psychiatry|
|Alternate Journal:||Early intervention in psychiatry|
|Abstract:||AIMS: This study aims to examine and compare the predictive utility of blood pressure (BP), waist circumference (WC) and body mass index (BMI), and to determine optimal cut-off values in prediction of metabolic syndrome (MetS) in patients with chronic schizophrenia. METHODS: About 100 patients with chronic schizophrenia were recruited. BMI and BP were measured and laboratory tests to evaluate patients' high-density lipoprotein cholesterol, triglycerides and glucose levels were performed. Presence of MetS was examined according to AHA/NHLBI guidelines. Predictive utility of BP, WC and BMI was examined using receiver operating curve and discriminant indices were determined accordingly. RESULTS: Forty-six (46%) patients were identified to have MetS. BMI of >/=23 kg m(-2) was most accurate (AUC = 0.83, P < 0.001), with sensitivity of 93.5%, specificity of 48.1%, positive predictive value of 60.6% and negative predictive value of 92.9% in identifying MetS. CONCLUSION: This finding has immediate and significant clinical implications in the local population with schizophrenia.|
Research Support, Non-U.S. Gov't
Early Interv Psychiatry. 2013 May
7(2):205-9. doi: 10.1111/j.1751-7893.2012.00384.x. Epub 2012 Jul 3.
|Authors Address:||Research Division, Institute of Mental Health, Singapore, Singapore.|
|Appears in Collections:||2013|
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