Title: Differences in psychiatric symptoms among Asian patients with depression: a multi-country cross-sectional study
year: 2014
Journal: Psychiatry Clin Neurosci
Volume: 68
Issue: 4
Pages: 245-54
Epubdate: 16/05/2014
date: Apr
Alternate Journal: Psychiatry and clinical neurosciences
ISSN: 1323-1316
Accession Number: 24829935
Abstract: AIM: The aim of this study was to compare the symptomatic and clinical features of depression among five groups of patients with major depressive disorder (MDD) living in China, Korea, Malaysia/Singapore, Taiwan, and Thailand. METHODS: Consecutive consenting adults (aged 18-65) who met DSM-IV criteria for non-psychotic MDD - based on the Mini International Neuropsychiatric Interview - and who were free of psychotropic medication were evaluated in a cross-sectional study. Depressive symptoms were evaluated using the 10-item Montgomery-Asberg Depression Rating Scale (MADRS) and the 13-item depression subscale of the Symptoms Checklist 90-Revised (SCL-90-R). In addition, the 10-item SCL-90-R Anxiety Subscale was completed. ancova were conducted, adjusting for confounders: age, completion of secondary education, marital status, work status, religion, index episode duration, and depressive severity. For the magnitude of differences, a threshold of 0.10 was taken as the minimum effect size representing clinical significance, and an effect size of 0.25 was considered moderate. RESULTS: Four MADRS symptoms differentiated these five groups, the most prominent being 'lassitude' and 'inner tension'. Nine SCL-90-R depression items also differentiated the groups, as did eight SCL-90-R Anxiety Subscale items. The MADRS lassitude item had the largest effect size (0.131). The rest of those statistically significant differences did not exceed 0.10. CONCLUSION: MDD is more similar than different among outpatients in these diverse Asian countries. The between-country differences, while present and not due to chance, are small enough to enable the use of common clinician and self-report rating scales in studies involving Asians with MDD from various ethnic backgrounds.
Notes: 1440-1819
Sulaiman, Ahmad H
Bautista, Dianne
Liu, Chia-Yih
Udomratn, Pichet
Bae, Jae Nam
Fang, Yiru
Chua, Hong C
Liu, Shen-Ing
George, Tom
Chan, Edwin
Tian-mei, Si
Hong, Jin Pyo
Srisurapanont, Manit
Rush, A John
Mood Disorders Research: Asian & Australian Network
Journal Article
Research Support, Non-U.S. Gov't
Psychiatry Clin Neurosci. 2014 Apr
URI: https://open-access.imh.com.sg/handle/123456789/4756
Translated author: NLM
Translated title: eng
Appears in Collections:2014

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