Title: What's in the pipeline? Drugs in development for autism spectrum disorder
year: 2014
Journal: Neuropsychiatr Dis Treat
Volume: 10
Pages: 371-81
Epubdate: 05/03/2014
Alternate Journal: Neuropsychiatric disease and treatment
ISSN: 1176-6328 (Print)
DOI: 10.2147/ndt.s39516
PMCID: PMC3934669
Accession Number: 24591832
Abstract: Autism Spectrum Disorder (ASD) is a complex neurodevelopmental disorder with both core symptoms and associated symptoms (eg, irritability, aggression, and comorbidities) that affect both the individual and the family/systems around them. There have been recent advances in the understanding of the underlying pathophysiology of ASD pertaining to genetics, epigenetics, neurological, hormonal, and environmental factors that contribute to the difficulties found in individuals with ASD. With this improved understanding, there has been a shift in the application of psychopharmacology in ASD and its related disorders. A literature review was conducted to examine research published in the last 5 years between different classes of psychotropic medications and ASD. The broad scope of the existing literature for the use of conventional medications is summarized and novel medications are discussed.
Notes: Sung, Min
Chin, Chee Hon
Lim, Choon Guan
Liew, Hwee Sen Alvin
Lim, Chau Sian
Kashala, Esperance
Weng, Shih-Jen
Journal Article
Review
New Zealand
Neuropsychiatr Dis Treat. 2014 Feb 20
10:371-81. doi: 10.2147/NDT.S39516. eCollection 2014.
URI: https://open-access.imh.com.sg/handle/123456789/4757
Authors Address: Department of Child and Adolescent Psychiatry, Institute of Mental Health, Singapore.
Department of Psychological Medicine, Khoo Teck Puat Hospital, Singapore.
Translated author: NLM
Translated title: eng
Appears in Collections:2014

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