|Title:||What's in the pipeline? Drugs in development for autism spectrum disorder|
|Journal:||Neuropsychiatr Dis Treat|
|Alternate Journal:||Neuropsychiatric disease and treatment|
|Abstract:||Autism Spectrum Disorder (ASD) is a complex neurodevelopmental disorder with both core symptoms and associated symptoms (eg, irritability, aggression, and comorbidities) that affect both the individual and the family/systems around them. There have been recent advances in the understanding of the underlying pathophysiology of ASD pertaining to genetics, epigenetics, neurological, hormonal, and environmental factors that contribute to the difficulties found in individuals with ASD. With this improved understanding, there has been a shift in the application of psychopharmacology in ASD and its related disorders. A literature review was conducted to examine research published in the last 5 years between different classes of psychotropic medications and ASD. The broad scope of the existing literature for the use of conventional medications is summarized and novel medications are discussed.|
Chin, Chee Hon
Lim, Choon Guan
Liew, Hwee Sen Alvin
Lim, Chau Sian
Neuropsychiatr Dis Treat. 2014 Feb 20
10:371-81. doi: 10.2147/NDT.S39516. eCollection 2014.
|Authors Address:||Department of Child and Adolescent Psychiatry, Institute of Mental Health, Singapore.|
Department of Psychological Medicine, Khoo Teck Puat Hospital, Singapore.
|Appears in Collections:||2014|
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