Title: Therapeutic Misconception in Psychiatry Research: A Systematic Review
year: 2016
Journal: Clin Psychopharmacol Neurosci
Volume: 14
Issue: 1
Pages: 17-25
Epubdate: 23/01/2016
date: 01/02/2029
Alternate Journal: Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology
ISSN: 1738-1088 (Print) 1738-1088
Legal note: PMC4730932
Article Number: 26792036
Keywords: Affective disorders Psychiatry Research Therapeutic misconception psychotic
Abstract: Therapeutic misconception (TM) denotes the phenomenon in which research subjects conflate research purpose, protocols and procedures with clinical treatment. We examined the prevalence, contributory factors, clinical associations, impact, and collated solutions on TM within psychiatric research, and made suggestions going ahead. Literature search for relevant empirical research papers was conducted until February 2015. Eighty-eight reports were extracted, of which 31 were selected, summarised into different headings for discussion of implications and collated solutions of TM. We found variable and high rates of TM (ranging from 12.5% to 86%) in some psychiatry research populations. Contributory factors to TM included perceived medical roles of researchers, media, research setting and subject factors. Greater TM in affective, neurodevelopmental and psychotic spectrum conditions were associated with demographic variables (such as lower education, increased age), clinical factors (such as poor insight, cognitive deficits, increased symptoms, poorer self-rated quality of health), and social functioning (such as decreased independence). Inattention to TM may lead to frustration, negative impression and abandonment of participation in psychiatry research. Strategies such as the employment of a neutral educator during the informed consent process and education modules may be effective in addressing TM. Further research is warranted to examine the different TM facets, specific clinical correlates and more effective management strategies.
Notes: Thong, Ivan Sk Foo, Meng Yee Sum, Min Yi Capps, Benjamin Lee, Tih-Shih Ho, Calvin Sim, Kang Journal Article Korea (South) Clin Psychopharmacol Neurosci. 2016 Feb 29;14(1):17-25. doi: 10.9758/cpn.2016.14.1.17.
URL: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4730932/pdf/cpn-14-017.pdf
URI: https://open-access.imh.com.sg/handle/123456789/5028
Authors Address: The College of Arts and Sciences, University at Buffalo, Buffalo, New York, USA. Research Division, Institute of Mental Health, Singapore, Singapore. Department of Bioethics, Faculty of Medicine, Dalhousie University, Halifax, Nova Scotia, Canada. Duke-NUS Graduate Medical School, Singapore, Singapore. Centre for Biomedical Ethics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore. Department of General Psychiatry, Institute of Mental Health, Singapore, Singapore.
Database Provider: NLM
language: eng
Appears in Collections:2016

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