|Title:||Typology of people with first-episode psychosis|
|Journal:||Early Interv Psychiatry|
|Alternate Journal:||Early intervention in psychiatry|
|Keywords:||cluster analysis first-episode psychosis functioning negative symptoms typology|
|Abstract:||AIMS: The aim of the current study was to create a typology of patients with first-episode psychosis based on sociodemographic and clinical characteristics, service use and outcomes using cluster analysis. METHODS: Data from all respondents who were accepted into the Early Psychosis Intervention Programme (EPIP), Singapore from 2007 to 2011 were analysed. A two-step clustering method was carried out to classify the patients into distinct clusters. RESULTS: Two clusters were identified. Cluster 1 comprised largely of younger people with mean age of 25.5 (6.0) years at treatment contact, who were predominantly male (55.3%), single (98.3%) and living with parents (86.3%). Cluster 1 had a higher proportion of people diagnosed with the schizophrenia spectrum disorder (71.4%) and with a positive family history of psychiatric illness. Patients in cluster 2 were generally older with a mean age of 33.6 (4.7) years and the majority were women (74.2%). Cluster 1 had people with higher Positive and Negative Syndrome Scale (PANSS) scores at baseline as compared with cluster 2. After a 1-year follow up, their scores were still poorer than their counterparts in cluster 2, especially for PANSS negative score. The functioning level of people in cluster 1 showed less improvement than the people in cluster 2 after a year of treatment. CONCLUSIONS: There is a compelling need to develop new therapies and intensively treat young people presenting with psychosis as this group tends to have poorer outcomes even after 1 year of treatment.|
|Notes:||1751-7893 Subramaniam, Mythily Zheng, Huili Soh, Pauline Poon, Lye Yin Vaingankar, Janhavi A Chong, Siow Ann Verma, Swapna Journal Article Australia Early Interv Psychiatry. 2016 Aug;10(4):346-54. doi: 10.1111/eip.12178. Epub 2014 Aug 29.|
|Authors Address:||Research Division, Institute of Mental Health, Singapore. Saw Swee Hock School of Public Health, Singapore. Department of Early Psychosis Intervention, Institute of Mental Health, Singapore.|
|Appears in Collections:||2016|
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