Title: Validation of the short version of the 10/66 dementia diagnosis in multiethnic Asian older adults in Singapore
year: 2017
Journal: BMC Geriatr
Volume: 17
Issue: 1
Pages: 94
date: 01/04/2021
ISSN: 1471-2318 (Electronic);1471-2318 (Linking)
Legal note: PMC5399400
Article Number: 28431511
Keywords: Aged;Aged, 80 and over;*Asian Continental Ancestry Group;Cross-Sectional Studies;Dementia/*diagnosis/epidemiology;Female;Humans;Male;Middle Aged;Prevalence;Singapore/epidemiology;*10/66 dementia;*Asian;*Concurrent validity;*Dementia;*Older adults;*Validity
Abstract: BACKGROUND: To validate the short version of the 10/66 dementia diagnosis against the standard version of the 10/66 dementia diagnosis and clinical diagnosis and examine concurrent validity with the World Health Organisation Disability Assessment schedule and care needs in a multiethnic Asian older adult population in Singapore. METHODS: Data from the Well-being of the Singapore Elderly study, a nationally representative survey of the older Singapore Resident population aged 60 years and above was used. The validity of the short version of the 10/66 dementia diagnostic criteria derived from the Community Screening Instrument for Dementia, the modified Consortium to Establish a Registry of Alzheimer's Disease 10-word list delayed recall and the EURO-D depression screen were examined against the standard version of the 10/66 dementia diagnosis and clinician diagnosis as a gold standard. Concurrent validity was tested by examining the relationships between the short version 10/66 dementia diagnosis, disability and care needs. RESULTS: A total of 2373 respondents who had completed data on the short version diagnosis were included in this study. The majority (82.63%) of respondents were of Chinese descent, 9.86% were Malays, 6.12% were of Indian descent and 1.39% belonged to other ethnic group. We found the short version 10/66 dementia diagnosis showed almost perfect agreement with the standard version 10/66 dementia diagnosis (kappa = 0.90, AUC = 0.96) and substantial agreement with clinical diagnosis (kappa = 0.70, AUC = 0.87). The weighted prevalence of dementia in the population was slightly higher based on the short version diagnosis than the standard version diagnosis (10.74% vs. 10.04%). We also found that those with the short version 10/66 dementia were significantly associated with higher disability (beta = 28.90, 95% CI = 23.62, 9.62) and needed care occasionally (OR =35.21, 95% CI = 18.08, 68.59) or much of the time (OR = 9.02, 95% CI = 5.21, 15.61). CONCLUSIONS: The study found that the short version 10/66 dementia diagnosis has excellent validity to diagnose dementia in a multiethnic Asian population in Singapore. Further research is required to determine the usefulness of this diagnosis in clinical practice or institutional settings to aid early detection and intervention for dementia.
Notes: Abdin, Edimansyah;Vaingankar, Janhavi Ajit;Picco, Louisa;Chua, Boon Yiang;Prince, Martin;Chong, Siow Ann;Subramaniam, Mythily;eng;Validation Studies;England;2017/04/23 06:00;BMC Geriatr. 2017 Apr 21;17(1):94. doi: 10.1186/s12877-017-0475-7.
URL: https://www.ncbi.nlm.nih.gov/pubmed/28431511;https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5399400/pdf/12877_2017_Article_475.pdf
URI: https://open-access.imh.com.sg/handle/123456789/5138
Authors Address: Research Division, Institute of Mental Health, Singapore, 539747, Singapore. Edimansyah_Abdin@imh.com.sg.;Research Division, Institute of Mental Health, Singapore, 539747, Singapore.;Health Service and Population Research Department, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.
Appears in Collections:2017

Files in This Item:
File Description SizeFormat 
Abdin-2017-Validation of the short version of.pdf404.2 kBAdobe PDFThumbnail
View/Open



Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.